| Gene Information | |
| NCBI Gene ID | 818028 |
| Symbol | GPPS/GPS1 |
| LocusTag | AT2G34630 |
| Synonyms | GERANYL DIPHOSPHATE SYNTHASE 1|GERANYLPYROPHOSPHATE SYNTHASE|GPPS|GPS1|T31E10.3|T31E10_3 |
| Description | GPPS/GPS1 (GERANYLPYROPHOSPHATE SYNTHASE); dimethylallyltranstransferase |
| Gene Type | protein-coding |
| Pattern | GPPS/GPS1|AT2G34630|GERANYL DIPHOSPHATE SYNTHASE 1|GERANYLPYROPHOSPHATE SYNTHASE|GPPS|GPS1|T31E10.3|T31E10_3|GPPS/GPS1 (GERANYLPYROPHOSPHATE SYNTHASE); dimethylallyltranstransferase |
| Corresponding sequence in Trichome EST library | AI485604 AM803527 AM812461 AM827973 AM836265 AW035690 AW218381 BE462767 BF518434 BG125274 BP906593 DB690501 DB693010 DB698282 DB698332 DQ286930 DY340280 DY340281 DY341719 EY041055 EY041056 EY050202 EY050203 EY078070 EY078071 FG138211 FG145324 FG152355 FG152415 FG165378 FG171867 FG171939 FG180534 FG191445 FG191538 FG193263 FG193353 FG638804 FS192828 FS205476 FS388023 FS409035 FS410914 GO603402 GO605149 GO608082 TCHL56559 TCNT57777 TCSL72225 TCSL72226 |
| Reference |
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Heterodimeric geranyl(geranyl)diphosphate synthase from hop (Humulus lupulus) and the evolution of monoterpene biosynthesis Wang G, Dixon RA. Proc Natl Acad Sci U S A 2009 Jun 16;106(24):9914-9 ...... Myrcene, which accounts for 30-50% of the essential oil in hop (Humulus lupulus L.) trichomes, derives from geranyl diphosphate (GPP), the common precursor of monoterpenes. Full-length sequences of heterodimeric GPP synthase small subunit (GPPS.SSU, belonging to the SSU I subfamily) and large subunit (LSU) cDNAs were mined from a hop trichome cDNA library. The SSU was inactive, whereas the LSU produced GPP, farnesyl diphosphate, and geranylgeranyl diphosphate (GGPP) from dimethylallyl diphosphate and isopentenyl diphosphate in vitro. Coexpression of both subunits in Escherichia coli yielded a heterodimeric enzyme exhibiting altered ratios of GPP and GGPP synthase activities and greatly enhanced catalytic efficiency. Transcript analysis suggested that the heterodimeric geranyl(geranyl)diphosphate synthase [G(G)PPS] is involved in myrcene biosynthesis in hop trichomes. ...... |