| Gene Information | |
| NCBI Gene ID | 818425 |
| Symbol | ITB1 |
| LocusTag | AT2G38440 |
| Synonyms | DIS3|DISTORTED3|IRREGULAR TRICHOME BRANCH1|SCAR2|T19C21.7|T19C21_7|WAVE4 |
| Description | ITB1 (IRREGULAR TRICHOME BRANCH1) |
| Gene Type | protein-coding |
| Pattern | ITB1|AT2G38440|DIS3|DISTORTED3|IRREGULAR TRICHOME BRANCH1|SCAR2|T19C21.7|T19C21_7|WAVE4|ITB1 (IRREGULAR TRICHOME BRANCH1) |
| Corresponding sequence in Trichome EST library | AM804583 AW092998 AW398446 BE325240 BE353992 BF650671 BG735238 CA990487 CX540325 DY331907 DY618247 EY478831 FG190639 HS081783 TCHL57726 TCMT47733 TCNT63646 TCOB41480 |
| Reference |
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IRREGULAR TRICHOME BRANCH1 in Arabidopsis encodes a plant homolog of the actin-related protein2/3 complex activator Scar/WAVE that regulates actin and microtubule organization. Zhang X, Dyachok J, Krishnakumar S, Smith LG, Oppenheimer DG. Plant Cell. 2005 Aug;17(8):2314-26. ...... in association with PIR121 and NAP1 to activate the Arp2/3 complex in Arabidopsis. In a screen for trichome branching defects, we isolated a mutant that showed irregularities in trichome branch positioning and expansion. We named this gene IRREGULAR TRICHOME BRANCH1 (ITB1). Positional cloning of the ITB1 gene showed that it encodes SCAR2, an Arabidopsis protein related to Scar/WAVE. Here, we show that itb1 mutants display cell expansion defects similar to those reported for the distorted class of ...... |
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DISTORTED3/SCAR2 is a putative arabidopsis WAVE complex subunit that activates the Arp2/3 complex and is required for epidermal morphogenesis. Basu D, Le J, El-Essal Sel-D, Huang S, Zhang C, Mallery EL, Koliantz G,Staiger CJ, Szymanski DB. Plant Cell. 2005 Feb;17(2):502-24. ...... to growth signals and external cues. The distorted group of trichome morphology mutants provides powerful genetic tools to study the control of actin filament nucleation in the context of morphogenesis. In this article, we report that DISTORTED3 (DIS3) encodes a plant-specific SCAR/WAVE homolog. Null alleles of DIS3, like those of other Arabidopsis thaliana WAVE and Actin-Related Protein (ARP) 2/3 subunit genes, cause trichome distortion, defects in cell-cell adhesion, and ...... |