DNA topoisomerase VI is essential for endoreduplication in Arabidopsis. Sugimoto-Shirasu K, Stacey NJ, Corsar J, Roberts K, McCann MC. Curr Biol. 2002 Oct 15;12(20):1782-6.
...... linked to endoreduplication, but the molecular mechanisms are poorly understood. We have used a genetic strategy to identify molecules involved in endocycles in Arabidopsis. We isolated two extreme dwarf mutants, hypocotyl6 (hyp6) and root hairless2 (rhl2) [3], and cells of these mutants successfully complete only the first two rounds of endoreduplication and stall at 8C. In both mutants, large cell types, such as trichomes and some epidermal cells, that normally endoreduplicate ......
|