Location:
Literature Mining
> Gene/Protein Citation
Gene Information |
NCBI Gene ID |
834671 |
Symbol |
KAS I |
LocusTag |
AT5G46290 |
Synonyms |
3-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE I|MPL12.7|MPL12_7 |
Description |
KAS I (3-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE I); fatty-acid synthase |
Gene Type |
protein-coding |
Pattern |
KAS I|AT5G46290|3-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE I|MPL12.7|MPL12_7|KAS I (3-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE I); fatty-acid synthase |
Corresponding sequence in Trichome EST library |
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Reference |
Transcriptomic and reverse genetic analyses of branched-chain fatty acid and acyl sugar production in Solanum pennellii and Nicotiana benthamiana. Slocombe SP, Schauvinhold I, McQuinn RP, Besser K, Welsby NA, Harper A, Aziz N, Li Y, Larson TR, Giovannoni J, Dixon RA, Broun P. Plant Physiol. 2008 Dec;148(4):1830-46. Epub 2008 Oct 17.
...... Functional analysis by down-regulation of specific KAS I genes and cerulenin inhibition indicated the involvement of the fatty acid synthase complex in BCFA production in S. pennellii. In summary, our study highlights both conserved and divergent mechanisms in the production of important defense compounds in Solanaceae and defines potential targets for engineering acyl sugar production in plants for improved pest tolerance.
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...... levels in trichomes of both species, and we show using virus-induced gene silencing that they are required for BCFA production in both cases and for acyl sugar synthesis in N. benthamiana. Functional analysis by down-regulation of specific KAS I genes and cerulenin inhibition indicated the involvement of the fatty acid synthase complex in BCFA production in S. pennellii. In summary, our study highlights both conserved and divergent mechanisms in the production of important defense ......
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