Gene Information
NCBI Gene ID 834671
Symbol KAS I
LocusTag AT5G46290
Synonyms 3-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE I|MPL12.7|MPL12_7
Description KAS I (3-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE I); fatty-acid synthase
Gene Type protein-coding
Pattern KAS I|AT5G46290|3-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE I|MPL12.7|MPL12_7|KAS I (3-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE I); fatty-acid synthase
Corresponding sequence in Trichome EST library

Reference

Transcriptomic and reverse genetic analyses of branched-chain fatty acid and acyl sugar production in Solanum pennellii and Nicotiana benthamiana.
Slocombe SP, Schauvinhold I, McQuinn RP, Besser K, Welsby NA, Harper A, Aziz N, Li Y, Larson TR, Giovannoni J, Dixon RA, Broun P. Plant Physiol. 2008 Dec;148(4):1830-46. Epub 2008 Oct 17.

...... Functional analysis by down-regulation of specific KAS I genes and cerulenin inhibition indicated the involvement of the fatty acid synthase complex in BCFA production in S. pennellii. In summary, our study highlights both conserved and divergent mechanisms in the production of important defense compounds in Solanaceae and defines potential targets for engineering acyl sugar production in plants for improved pest tolerance. ......


...... levels in trichomes of both species, and we show using virus-induced gene silencing that they are required for BCFA production in both cases and for acyl sugar synthesis in N. benthamiana. Functional analysis by down-regulation of specific KAS I genes and cerulenin inhibition indicated the involvement of the fatty acid synthase complex in BCFA production in S. pennellii. In summary, our study highlights both conserved and divergent mechanisms in the production of important defense ......